ACOT7

ACOT7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2QQ2
Identifiers
Aliases	ACOT7, ACH1, ACT, BACH, CTE-II, LACH, LACH1, hBACH, acyl-CoA thioesterase 7
External IDs	MGI: 1917275 HomoloGene: 15780 GeneCards: ACOT7
Gene location (Human) Chr. Chromosome 1 (human) Band 1p36.31 Start 6,264,269 bp End 6,394,391 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 E2 Start 152,178,134 bp End 152,271,855 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • palmitoyl-CoA hydrolase activity • fatty-acyl-CoA binding • protein homodimerization activity • carboxylic ester hydrolase activity • long-chain fatty acyl-CoA binding • protein binding • hydrolase activity • acyl-CoA hydrolase activity • myristoyl-CoA hydrolase activity Cellular component • cytosol • nucleoplasm • mitochondrion • extracellular exosome • cytoplasm Biological process • medium-chain fatty acid biosynthetic process • medium-chain fatty-acyl-CoA catabolic process • long-chain fatty-acyl-CoA catabolic process • coenzyme A biosynthetic process • palmitic acid biosynthetic process • acyl-CoA metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	11332	70025
Ensembl	ENSG00000097021	ENSMUSG00000028937
UniProt	O00154	Q91V12
RefSeq (mRNA)	NM_181866 NM_007274 NM_181862 NM_181863 NM_181864 NM_181865	NM_001146057 NM_001146058 NM_133348
RefSeq (protein)	NP_009205 NP_863654 NP_863655 NP_863656	NP_001139529 NP_001139530 NP_579926
Location (UCSC)	Chr 1: 6.26 – 6.39 Mb	Chr 1: 152.18 – 152.27 Mb
PubMed search

2QQ2

11332

70025

ENSG00000097021

ENSMUSG00000028937

O00154

Q91V12

NM_181865

NM_001146057
NM_001146058
NM_133348

NP_009205
NP_863654
NP_863655
NP_863656

NP_001139529
NP_001139530
NP_579926

Cytosolic acyl coenzyme A thioester hydrolase is an enzyme that in humans is encoded by the ACOT7 gene.

This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized.

...
Wikipedia