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Axel Brunger

Axel T. Brunger
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Axel T. Brunger (born November 25, 1956) is a German American biophysicist. He is Professor of Molecular and Cellular Physiology, and Neurology, of Photon Science and, by courtesy, of Structural Biology at Stanford University, and a Howard Hughes Medical Institute Investigator. He also is currently serving as the Chair of the Department of Molecular and Cellular Physiology (2013-present).

Brunger was born in Leipzig, Germany on November 25, 1956. He graduated with a degree in Physics and Mathematics from the University of Hamburg in 1977. He completed his Diplom in Physics from the University of Hamburg in 1980. He completed his PhD in Biophysics from Technical University of Munich in 1982, advised by Klaus Schulten.

Brunger held a NATO postdoctoral fellowship to work with Martin Karplus at Harvard University, where he subsequently became a research associate in the Department of Chemistry after a brief return to Germany. He joined the Molecular Biophysics and Biochemistry department at Yale University in 1987 and moved to Stanford University in 2000. Brunger was elected to the United States National Academy of Sciences in 2005 and won the inaugural DeLano Award for Computational Biosciences in 2011.

Brunger is known for developing a computer program called CNS used for solving structures based on X-ray diffraction or solution NMR data, which was first released in 1992. The program is a major extension of a 1987 program developed with John Kuriyan and Karplus called X-PLOR, whose original inspiration was motivated by Marius Clore's efforts in interpreting NMR data and which has been extended by Clore's continued development of XPLOR-NIH.


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