B3 DNA binding domain
| B3 DNA binding domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
B3 DNA binding domain of RAV1
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| Identifiers | |||||||||
| Symbol | B3_domain | ||||||||
| Pfam | PF02362 | ||||||||
| InterPro | IPR003340 | ||||||||
| PROSITE | PS50863 | ||||||||
| SCOP | 1wid | ||||||||
| SUPERFAMILY | 1wid | ||||||||
| CDD | cd10017 | ||||||||
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| Available protein structures: | |
|---|---|
| Pfam | structures |
| PDB | RCSB PDB; PDBe; PDBj |
| PDBsum | structure summary |
The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors, from higher plants (≥40 species) (Pfam PF02362) combined with other domains (InterPro: IPR003340). It consists of 100-120 residues, includes seven beta strands and two alpha helices that form a DNA-binding pseudobarrel protein fold (SCOP 117343); it interacts with the major groove of DNA.
In Arabidopsis thaliana, there are three main families of transcription factors that contain B3 domain:
PDB: 1WID and PDB: 1YEL are only known NMR solution phase structures of the B3 DNA Binding Domain.
The N-terminal domain of restriction endonuclease EcoRII; the C-terminal domain of restriction endonuclease BfiI possess a similar DNA-binding pseudobarrel protein fold.
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