CD86

CD86

CD86 structure.gif

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1I85, 1NCN

Identifiers

CD86, B7-2, B7.2, B70, CD28LG2, LAB72, CD86 molecule

External IDs

OMIM: 601020 MGI: 101773 HomoloGene: 10443 GeneCards: CD86

Gene ontology
Molecular function	• coreceptor activity • virus receptor activity • protein binding • receptor binding • receptor activity • phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Cellular component	• integral component of membrane • intracellular membrane-bounded organelle • membrane • plasma membrane • cell surface • extracellular exosome • external side of plasma membrane
Biological process	• response to yeast • adaptive immune response • response to interferon-gamma • immune system process • cell-cell signaling • T cell costimulation • aging • myeloid dendritic cell differentiation • cellular response to cytokine stimulus • T cell proliferation involved in immune response • positive regulation of interleukin-2 biosynthetic process • toll-like receptor signaling pathway • positive regulation of transcription, DNA-templated • B cell activation • response to lipopolysaccharide • cellular response to metal ion • negative regulation of T cell anergy • defense response to virus • immune response • positive regulation of T cell proliferation • positive regulation of cell proliferation • positive regulation of T-helper 2 cell differentiation • viral entry into host cell • viral process • positive regulation of lymphotoxin A biosynthetic process • toll-like receptor 3 signaling pathway • cellular response to lipopolysaccharide • T cell activation • response to drug • phosphatidylinositol-mediated signaling • positive regulation of interleukin-4 biosynthetic process • positive regulation of activated T cell proliferation • regulation of phosphatidylinositol 3-kinase signaling • phosphatidylinositol phosphorylation
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CD86 210895 s at fs.png

PBB GE CD86 205685 at fs.png

PBB GE CD86 205686 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


942


12524


ENSG00000114013


ENSMUSG00000022901


P42081


P42082

RefSeq (mRNA)


NM_176892 NM_001206924 NM_001206925 NM_006889 NM_175862


NM_019388

RefSeq (protein)


NP_001193853 NP_001193854 NP_008820 NP_787058 NP_795711


NP_062261.3 NP_062261

Location (UCSC)

Chr 3: 122.06 – 122.12 Mb

Chr 16: 36.6 – 36.67 Mb

PubMed search

ENSG00000114013

ENSMUSG00000022901

NM_176892
NM_001206924
NM_001206925
NM_006889
NM_175862

NP_001193853
NP_001193854
NP_008820
NP_787058
NP_795711

NP_062261.3
NP_062261

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Wikipedia

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