CDK8

CDK8
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3RGF, 4F6S, 4F6U, 4F6W, 4F70, 4F7J, 4F7L, 4F7N, 4F7S, 4G6L, 4CRL, 5HBH, 5CEI, 5FGK, 5HBE, 5BNJ, 5HBJ, 5HVY, 5HNB, 5I5Z
Identifiers
Aliases	CDK8, K35, cyclin-dependent kinase 8, cyclin dependent kinase 8
External IDs	MGI: 1196224 HomoloGene: 55565 GeneCards: CDK8
Gene ontology Molecular function • transferase activity • protein kinase activity • nucleotide binding • kinase activity • protein binding • RNA polymerase II carboxy-terminal domain kinase activity • ATP binding • protein serine/threonine kinase activity • cyclin-dependent protein serine/threonine kinase activity Cellular component • mediator complex • nucleoplasm • Q40260 • nucleolus • protein complex Biological process • regulation of transcription, DNA-templated • phosphorylation • protein phosphorylation • transcription initiation from RNA polymerase II promoter • positive regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • regulation of mitotic cell cycle Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1024	264064
Ensembl	ENSG00000132964	ENSMUSG00000029635
UniProt	P49336	Q8R3L8
RefSeq (mRNA)	NM_001260 NM_001318368 NM_001346501	NM_153599 NM_181570
RefSeq (protein)	NP_001251 NP_001305297 NP_001333430	NP_705827
Location (UCSC)	Chr 13: 26.25 – 26.41 Mb	Chr 5: 146.23 – 146.3 Mb
PubMed search

3RGF, 4F6S, 4F6U, 4F6W, 4F70, 4F7J, 4F7L, 4F7N, 4F7S, 4G6L, 4CRL, 5HBH, 5CEI, 5FGK, 5HBE, 5BNJ, 5HBJ, 5HVY, 5HNB, 5I5Z

1024

264064

ENSG00000132964

ENSMUSG00000029635

...
Wikipedia