| caspase 5, apoptosis-related cysteine peptidase | |
|---|---|
| Identifiers | |
| Symbol | CASP5 |
| Alt. symbols | ICE(rel)III, ICH3 |
| Entrez | 838 |
| HUGO | 1506 |
| OMIM | 602665 |
| RefSeq | NM_004347 |
| UniProt | P51878 |
| Other data | |
| EC number | 3.4.22.58 |
| Locus | Chr. 11 q22.2-q22.3 |
Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.