| Total population | |
|---|---|
| (316,049 enrolled tribal members | |
| Regions with significant populations | |
| 
  Tennessee 5,296 (0.1%) | |
| Languages | |
| English, Cherokee | |
| Religion | |
| Christianity, Kituhwa, Four Mothers Society,Native American Church | 
(316,049 enrolled tribal members
(Eastern Band: 13,000+,Cherokee Nation: 288,749, United Keetoowah Band: 14,300)
 United States
 United States Georgia 5,897 (0.1%)
 Georgia 5,897 (0.1%) North Carolina 16,158 (0.2%)
 North Carolina 16,158 (0.2%) Oklahoma 102,580 (2.7%)
 Oklahoma 102,580 (2.7%) South Carolina 3,482 (0.1%)
 South Carolina 3,482 (0.1%)