Corneodesmosin

CDSN
Identifiers
Aliases	CDSN, D6S586E, HTSS, HTSS1, HYPT2, PSS, S, PSS1, corneodesmosin
External IDs	HomoloGene: 48005 GeneCards: CDSN
Gene ontology Molecular function • protein homodimerization activity Cellular component • extracellular region • desmosome • extracellular exosome • cell-cell junction • cornified envelope • plasma membrane Biological process • single organismal cell-cell adhesion • cell adhesion • skin morphogenesis • keratinocyte differentiation • epidermis development • cornification Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1041	n/a
Ensembl	n/a	n/a
UniProt	Q15517	n/a
RefSeq (mRNA)	NM_001264	n/a
RefSeq (protein)	NP_001255	n/a
Location (UCSC)	Chr 6: 31.12 – 31.12 Mb	n/a
PubMed search		n/a

1041

n/a

n/a

n/a

Q15517

n/a

NM_001264

n/a

NP_001255

n/a

Corneodesmosin is a protein that in humans is encoded by the CDSN gene.

This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. During maturation of the cornified layers, the protein undergoes a series of cleavages, which are thought to be required for desquamation. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.

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Wikipedia