Cyclin-dependent kinase inhibitor
| Cyclin-dependent kinase inhibitor | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.
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| Identifiers | |||||||||
| Symbol | CDI | ||||||||
| Pfam | PF02234 | ||||||||
| InterPro | IPR003175 | ||||||||
| SCOP | 1jsu | ||||||||
| SUPERFAMILY | 1jsu | ||||||||
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| Available protein structures: | |
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| Pfam | structures |
| PDB | RCSB PDB; PDBe; PDBj |
| PDBsum | structure summary |
A cyclin-dependent kinase inhibitor protein is a protein which inhibits cyclin-dependent kinase. Several function as tumor suppressor proteins. Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (called CDIs, CKIs or CDKIs). CDIs are involved in cell cycle arrest at the G1 phase.
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