DAPK1

DAPK1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1IG1, 1JKK, 1JKL, 1JKS, 1JKT, 1P4F, 1WVX, 1WVY, 1YR5, 2W4J, 2W4K, 2X0G, 2XUU, 2XZS, 2Y0A, 2Y4P, 2Y4V, 2YAK, 3DFC, 3DGK, 3EH9, 3EHA, 3F5G, 3F5U, 3GU4, 3GU5, 3GU6, 3GU7, 3GU8, 3GUB, 3ZXT, 4B4L, 4PF4, 4TL0, 4TXC, 4UV0, 4YO4, 4YPD, 5AUW, 5AUU, 5AV1, 5AUY, 5AUT, 5AUX, 5AUV, 5AUZ, 5AV0, 5AV4, 5AV2, 5AV3
Identifiers
Aliases	DAPK1, DAPK, death associated protein kinase 1, ROCO3
External IDs	MGI: 1916885 HomoloGene: 3626 GeneCards: DAPK1
Gene location (Human) Chr. Chromosome 9 (human) Band 9q21.33 Start 87,497,228 bp End 87,708,633 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band n/a Start 60,601,947 bp End 60,763,185 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • transferase activity • nucleotide binding • GTP binding • syntaxin-1 binding • kinase activity • protein binding • identical protein binding • calmodulin-dependent protein kinase activity • protein serine/threonine kinase activity • calmodulin binding • ATP binding • protein kinase activity Cellular component • plasma • actin cytoskeleton • cytoskeleton • cytoplasm Biological process • regulation of apoptotic process • negative regulation of translation • phosphorylation • negative regulation of apoptotic process • positive regulation of cysteine-type endopeptidase activity involved in apoptotic process • regulation of autophagy • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • apoptotic signaling pathway • protein autophosphorylation • regulation of translation • extrinsic apoptotic signaling pathway via death domain receptors • signal transduction • apoptotic process • regulation of NMDA receptor activity • protein phosphorylation • positive regulation of autophagy • intracellular signal transduction • cellular response to interferon-gamma • cellular response to hydroperoxide Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	1612	69635
Ensembl	ENSG00000196730	ENSMUSG00000021559
UniProt	P53355	Q80YE7
RefSeq (mRNA)	NM_001288729 NM_001288730 NM_001288731 NM_004938	NM_001285917 NM_029653 NM_134062
RefSeq (protein)	NP_001275658 NP_001275659 NP_001275660 NP_004929	NP_001272846 NP_083929 NP_598823
Location (UCSC)	Chr 9: 87.5 – 87.71 Mb	Chr 9: 60.6 – 60.76 Mb
PubMed search

1IG1, 1JKK, 1JKL, 1JKS, 1JKT, 1P4F, 1WVX, 1WVY, 1YR5, 2W4J, 2W4K, 2X0G, 2XUU, 2XZS, 2Y0A, 2Y4P, 2Y4V, 2YAK, 3DFC, 3DGK, 3EH9, 3EHA, 3F5G, 3F5U, 3GU4, 3GU5, 3GU6, 3GU7, 3GU8, 3GUB, 3ZXT, 4B4L, 4PF4, 4TL0, 4TXC, 4UV0, 4YO4, 4YPD, 5AUW, 5AUU, 5AV1, 5AUY, 5AUT, 5AUX, 5AUV, 5AUZ, 5AV0, 5AV4, 5AV2, 5AV3

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