Deoxyadenosine

Deoxyadenosine

Names
IUPAC name 5-(6-Aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Other names 2'-Deoxyadenosine; α-Deoxyadenosine; dA
Identifiers
CAS Number	958-09-8 Y
3D model (Jmol)	Interactive image
ChEBI	CHEBI:17256 Y
ChemSpider	13135 Y
ECHA InfoCard	100.012.262
IUPHAR/BPS	5109
MeSH	2'-deoxyadenosine
PubChem CID	636
UNII	P582C98ULC Y
InChI InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1 Y Key: OLXZPDWKRNYJJZ-RRKCRQDMSA-N Y InChI=1/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1 Key: OLXZPDWKRNYJJZ-RRKCRQDMBK
SMILES n2c1c(ncnc1n(c2)[C@@H]3O[C@@H]([C@@H](O)C3)CO)N
Properties
Chemical formula	C10H13N5O3
Molar mass	251.24192
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

Deoxyadenosine (symbol dA or dAdo) is a deoxyribonucleoside. It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety. Deoxyadenosine is the DNA nucleoside A, which pairs with deoxythymidine (T) in double-stranded DNA.

In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).