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Diamine oxidase

Diamine oxidase
Crystal Structure of Human Diamine Oxidase.png
Ribbon representation of human diamine oxidase (rendered with PyMOL)
Identifiers
EC number 1.4.3.22
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

Diamine oxidase, also known as histaminase, is an enzyme (EC 1.4.3.22) involved in the metabolism, oxidation, and inactivation of histamine in animals. Highest content is observed in the digestive tract and placenta. It is also secreted by eosinophils. In case of a shortage of diamine oxidase in the human body, it may appear as an allergy or histamine intolerance.

Diamine oxidase should not be confused with D-amino acid oxidase as they are both sometimes referred to as DAO.



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Wikipedia

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