"Don't Leave Me This Way" is a song written by Kenneth Gamble, Leon Huff and Cary Gilbert. First charting as a hit for Harold Melvin & the Blue Notes, an act on Gamble & Huff's Philadelphia International label in 1975, "Don't Leave Me This Way" was later a huge disco hit for Motown artist Thelma Houston in 1977. The song was also a major hit for British group The Communards in 1986.

The Blue Notes' original version of the song, featuring Teddy Pendergrass' lead vocal, was included as an album track on the group's successful album Wake Up Everybody released in November 1975. Though not issued as a single in the United States at the time, the Blue Notes' recording reached #3 on the US Billboard Disco Chart in the wake of Thelma Houston's version. The song proved to be the group's biggest hit in the UK, #5 on the UK singles chart, when released there as a single in 1977. It became the title track of a budget LP issued on the CBS Embassy label in the UK in 1978.> The track was finally issued as a 12-inch single in the US in 1979, coupled with "Bad Luck".

"Don't Leave Me This Way" was covered by Motown in 1976. Originally assigned to Diana Ross, it was intended to be the follow-up to her hit "Love Hangover" but was reassigned and given to the upcoming Motown artist Thelma Houston instead. Studio musicians on the track included James Gadson on drums, Henry E. Davis (of the band L.T.D.) on bass, and John Barnes on keyboards.

Following the release of her third album Any Way You Like It, a Boston record pool unanimously reported positive audience response to "Don't Leave Me This Way" in discos, and the song was selected for release as a single. Houston's version became a massive international hit, topping the soul singles chart and, nine weeks later, the Billboard Hot 100 for one week in April 1977. The song peaked at #13 in the UK. The song went to number one on the disco chart. Later in the year, it was featured on the soundtrack of the movie, Looking for Mr. Goodbar. In 1978, "Don't Leave Me This Way" won the award for Best R&B Vocal Performance, Female at the 20th Annual Grammy Awards.

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