| HBQ1 | |||||||||||||||||
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| Aliases | HBQ1, HBQ, hemoglobin subunit theta 1 | ||||||||||||||||
| External IDs | MGI: 3613460 HomoloGene: 3895 GeneCards: HBQ1 | ||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||
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| Location (UCSC) | Chr 16: 0.18 – 0.18 Mb | Chr 11: 32.29 – 32.29 Mb | |||||||||||||||
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Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene.
Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue.