HIP1R

HIP1R
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1R0D
Identifiers
Aliases	HIP1R, HIP12, HIP3, ILWEQ, huntingtin interacting protein 1 related
External IDs	MGI: 1352504 HomoloGene: 78348 GeneCards: HIP1R
Gene location (Human) Chr. Chromosome 12 (human) Band 12q24.31 Start 122,834,453 bp End 122,862,960 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band 5|5 F Start 123,973,628 bp End 124,005,558 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • actin binding • protein binding • phospholipid binding • phosphatidylinositol binding • phosphatidylinositol-4,5-bisphosphate binding • phosphatidylinositol-3,4,5-trisphosphate binding • SH3 domain binding • clathrin binding • clathrin light chain binding • clathrin adaptor activity • protein homodimerization activity • phosphatidylinositol-3,4-bisphosphate binding • protein heterodimerization activity • actin filament binding • phosphatidylinositol-3,5-bisphosphate binding • identical protein binding Cellular component • perinuclear region of cytoplasm • clathrin-coated pit • cytoskeleton • clathrin-coated vesicle membrane • intracellular membrane-bounded organelle • endomembrane system • membrane • cytoplasmic vesicle • clathrin-coated vesicle • cytoplasm • mitochondrion • cytosol • cell cortex • postsynaptic density • apical plasma membrane • ruffle membrane • dendrite cytoplasm • neuronal cell body • dendritic spine • synaptic membrane Biological process • clathrin-dependent endocytosis • endocytosis • receptor-mediated endocytosis • apoptotic process • activation of cysteine-type endopeptidase activity involved in apoptotic process • regulation of endocytosis • negative regulation of actin filament polymerization • positive regulation of protein binding • regulation of actin cytoskeleton organization • negative regulation of Arp2/3 complex-mediated actin nucleation • positive regulation of apoptotic process • negative regulation of apoptotic process • positive regulation of epidermal growth factor receptor signaling pathway • clathrin coat assembly • protein stabilization • digestive system development • regulation of gastric acid secretion • membrane organization • positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway • positive regulation of clathrin coat assembly • regulation of clathrin-dependent endocytosis • positive regulation of platelet-derived growth factor receptor-beta signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9026	29816
Ensembl	ENSG00000130787	ENSMUSG00000000915
UniProt	O75146	Q9JKY5
RefSeq (mRNA)	NM_001303097 NM_001303099 NM_003959	NM_145070
RefSeq (protein)	NP_001290026 NP_001290028 NP_003950	NP_659507
Location (UCSC)	Chr 12: 122.83 – 122.86 Mb	Chr 12: 123.97 – 124.01 Mb
PubMed search

1R0D

9026

29816

ENSG00000130787

ENSMUSG00000000915

O75146

Q9JKY5

NM_001303097
NM_001303099
NM_003959

NM_145070

NP_001290026
NP_001290028
NP_003950

NP_659507

Huntingtin-interacting protein 1-related protein is a protein that in humans is encoded by the HIP1R gene.

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