Interferon gamma receptor 1

IFNGR1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1FG9, 1FYH, 1JRH
Identifiers
Aliases	IFNGR1, CD119, IFNGR, IMD27A, IMD27B, interferon gamma receptor 1
External IDs	MGI: 107655 HomoloGene: 359 GeneCards: IFNGR1
Gene ontology Molecular function • interferon-gamma receptor activity • protein binding • cytokine binding Cellular component • integral component of membrane • integral component of plasma membrane • membrane • postsynaptic density of dendrite • vesicle • dendrite • endoplasmic reticulum • plasma membrane • intracellular membrane-bounded organelle Biological process • response to virus • regulation of interferon-gamma-mediated signaling pathway • signal transduction • interferon-gamma-mediated signaling pathway • defense response to virus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3459	15979
Ensembl	ENSG00000027697	ENSMUSG00000020009
UniProt	P15260	P15261
RefSeq (mRNA)	NM_000416	NM_010511
RefSeq (protein)	NP_000407	NP_034641
Location (UCSC)	Chr 6: 137.2 – 137.22 Mb	Chr 10: 19.59 – 19.61 Mb
PubMed search

1FG9, 1FYH, 1JRH

3459

15979

ENSG00000027697

ENSMUSG00000020009

P15260

P15261

NM_000416

NM_010511

NP_000407

NP_034641

Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene.

IFNGR1 encodes the ligand-binding chain (alpha) of the heterodimeric gamma interferon receptor, which is found on macrophages. IFNGR2 encodes the non-ligand-binding partner of the heterodimeric receptor.

Interferon gamma receptor 1 has been shown to interact with Interferon-gamma.

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Wikipedia