Interleukin-7

IL7

Protein IL7 PDB 1IL7.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3DI2, 3DI3

Identifiers

IL7, IL-7, interleukin 7

External IDs

OMIM: 146660 MGI: 96561 HomoloGene: 680 GeneCards: IL7

Gene ontology
Molecular function	• protein binding • interleukin-7 receptor binding • growth factor activity • cytokine receptor binding • cytokine activity
Cellular component	• extracellular region • extracellular space
Biological process	• negative regulation of catalytic activity • cell-cell signaling • negative regulation of extrinsic apoptotic signaling pathway • positive regulation of organ growth • negative regulation of apoptotic process • bone resorption • humoral immune response • immune response • positive regulation of cell proliferation • animal organ morphogenesis • regulation of gene expression • homeostasis of number of cells within a tissue • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand • T cell lineage commitment • positive regulation of B cell proliferation • positive regulation of T cell differentiation
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE IL7 206693 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


3574


16196


ENSG00000104432


ENSMUSG00000040329


P13232


P10168

RefSeq (mRNA)


NM_000880 NM_001199886 NM_001199887 NM_001199888


NM_008371 NM_001313888 NM_001313889 NM_001313890

RefSeq (protein)


NP_000871 NP_001186815 NP_001186816 NP_001186817


NP_032397.1 NP_001300817 NP_001300818 NP_001300819 NP_032397

Location (UCSC)

Chr 8: 78.68 – 78.81 Mb

Chr 3: 7.57 – 7.61 Mb

PubMed search

ENSG00000104432

ENSMUSG00000040329

NM_000880
NM_001199886
NM_001199887
NM_001199888

NM_008371
NM_001313888
NM_001313889
NM_001313890

NP_000871
NP_001186815
NP_001186816
NP_001186817

NP_032397.1
NP_001300817
NP_001300818
NP_001300819
NP_032397

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Wikipedia

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