KLK-4

KLK4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2BDG, 2BDH, 2BDI, 4K1E, 4K8Y, 4KEL, 4KGA
Identifiers
Aliases	KLK4, AI2A1, ARM1, EMSP, EMSP1, KLK-L1, PRSS17, PSTS, kallikrein, kallikrein related peptidase 4
External IDs	MGI: 1861379 HomoloGene: 55856 GeneCards: KLK4
Gene ontology Molecular function • peptidase activity • serine-type peptidase activity • protein binding • hydrolase activity • metal ion binding • serine-type endopeptidase activity Cellular component • extracellular region Biological process • proteolysis • amelogenesis • biomineral tissue development Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9622	56640
Ensembl	ENSG00000167749	ENSMUSG00000006948
UniProt	Q9Y5K2	Q9Z0M1
RefSeq (mRNA)	NM_001302961 NM_004917	NM_019928
RefSeq (protein)	NP_001289890 NP_004908	NP_064312
Location (UCSC)	Chr 19: 50.91 – 50.91 Mb	Chr 7: 43.88 – 43.89 Mb
PubMed search

2BDG, 2BDH, 2BDI, 4K1E, 4K8Y, 4KEL, 4KGA

9622

56640

ENSG00000167749

ENSMUSG00000006948

Q9Y5K2

Q9Z0M1

NM_001302961
NM_004917

NM_019928

NP_001289890
NP_004908

NP_064312

Kallikrein-related peptidase 4 is a protein which in humans is encoded by the KLK4 gene.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer.

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Wikipedia