LPCAT1

LPCAT1
Identifiers
Aliases	LPCAT1, lysophosphatidylcholine acyltransferase 1, AYTL2, PFAAP3, lpcat, AGPAT10, AGPAT9, LPCAT-1, lysoPAFAT
External IDs	MGI: 2384812 HomoloGene: 9871 GeneCards: LPCAT1
EC number	2.3.1.67
Gene location (Human) Chr. Chromosome 5 (human) Band No data available Start 1,456,480 bp End 1,523,977 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band No data available Start 73,467,197 bp End 73,516,422 bp
Gene ontology Molecular function • 1-alkylglycerophosphocholine O-acyltransferase activity • metal ion binding • calcium ion binding • transferase activity • transferase activity, transferring acyl groups • 1-alkylglycerophosphocholine O-acetyltransferase activity • 1-alkenylglycerophosphocholine O-acyltransferase activity • 1-acylglycerophosphocholine O-acyltransferase activity • 1-acylglycerol-3-phosphate O-acyltransferase activity • 2-acylglycerol-3-phosphate O-acyltransferase activity Cellular component • integral component of membrane • Golgi apparatus • Golgi membrane • membrane • lipid droplet • endoplasmic reticulum membrane • endoplasmic reticulum • plasma membrane • azurophil granule membrane Biological process • phospholipid biosynthetic process • retina development in camera-type eye • lipid metabolic process • phosphatidylglycerol acyl-chain remodeling • positive regulation of protein catabolic process • phosphatidic acid biosynthetic process • metabolic process • surfactant homeostasis • negative regulation of phosphatidylcholine biosynthetic process • phosphatidylcholine acyl-chain remodeling • phospholipid metabolic process • phosphatidylcholine biosynthetic process • neutrophil degranulation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79888	210992
Ensembl	ENSG00000275079 ENSG00000153395	ENSMUSG00000021608
UniProt	Q8NF37	Q3TFD2
RefSeq (mRNA)	NM_024830	NM_145376
RefSeq (protein)	NP_079106	NP_663351
Location (UCSC)	Chr 5: 1.46 – 1.52 Mb	Chr 5: 73.47 – 73.52 Mb
PubMed search

79888

210992

ENSG00000275079
ENSG00000153395

ENSMUSG00000021608

Q8NF37

Q3TFD2

NM_024830

NM_145376

NP_079106

NP_663351

Lysophosphatidylcholine acyltransferase 1 is a protein in humans that is encoded by the LPCAT1 gene.

Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis.

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Wikipedia