Luzindole

Luzindole
Clinical data

ATC code	None
Legal status
Legal status	Non-regulated
Identifiers
IUPAC name N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide
CAS Number	117946-91-5
PubChem (CID)	122162
ChemSpider	108959
ChEBI	CHEBI:131788^Y
Chemical and physical data
Formula	C₁₉H₂₀N₂O
Molar mass	292.375 g/mol
3D model (Jmol)	Interactive image
SMILES O=C(NCCc2c1ccccc1nc2Cc3ccccc3)C
InChI InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22) Key:WVVXBPKOIZGVNS-UHFFFAOYSA-N

Luzindole (N-0774), (N-acetyl-2-benzyltryptamine), is a drug used in scientific research to study the role of melatonin in the body. Luzindole acts as a selective melatonin receptor antagonist, with approximately 11- to 25-fold greater affinity for the MT₂ over the MT₁ receptor. In animal studies, it has been observed to disrupt the circadian rhythm as well as produce antidepressant effects.