Malate dehydrogenase 2

MDH2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DFD, 4WLE, 4WLO, 4WLV, 4WLN, 4WLU, 4WLF
Identifiers
Aliases	MDH2, M-MDH, MDH, MGC:3559, MOR1, Malate dehydrogenase 2, EIEE51
External IDs	MGI: 97050 HomoloGene: 55938 GeneCards: MDH2
Gene location (Human) Chr. Chromosome 7 (human) Band n/a Start 76,048,051 bp End 76,067,508 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band n/a Start 135,778,480 bp End 135,790,398 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor • malate dehydrogenase activity • protein self-association • catalytic activity • L-malate dehydrogenase activity • oxidoreductase activity • malate dehydrogenase (NADP+) activity • RNA binding Cellular component • membrane • myelin sheath • mitochondrial matrix • mitochondrion • mitochondrial inner membrane • extracellular exosome • nucleus Biological process • gluconeogenesis • malate metabolic process • carboxylic acid metabolic process • internal protein amino acid acetylation • tricarboxylic acid cycle • oxaloacetate metabolic process • NADH metabolic process • oxidation-reduction process • Q14762260 • aerobic respiration Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4191	17448
Ensembl	ENSG00000146701	ENSMUSG00000019179
UniProt	P40926	P08249
RefSeq (mRNA)	NM_001282403 NM_001282404 NM_005918	NM_008617
RefSeq (protein)	NP_001269332 NP_001269333 NP_005909	NP_032643
Location (UCSC)	Chr 7: 76.05 – 76.07 Mb	Chr 7: 135.78 – 135.79 Mb
PubMed search

2DFD, 4WLE, 4WLO, 4WLV, 4WLN, 4WLU, 4WLF

4191

17448

ENSG00000146701

ENSMUSG00000019179

P40926

P08249

NM_001282403
NM_001282404
NM_005918

NM_008617

NP_001269332
NP_001269333
NP_005909

NP_032643

Malate dehydrogenase, mitochondrial also known as malate dehydrogenase 2 is an enzyme that in humans is encoded by the MDH2 gene.

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