Mithridates V Euergetes (Greek: Μιθριδάτης ὁ εὐεργέτης, which means "Mithridates the benefactor"; flourished 2nd century BC, reigned 150–120 BC); also known as Mithridates V of Pontus, Mithradates V of Pontus and Mithradates V Euergetes, was a Prince and seventh King of the wealthy Kingdom of Pontus.
Mithridates V was of Greek Macedonian and Persian ancestry. He was the son of the King Pharnaces I of Pontus and Queen Nysa, while his sister was Nysa of Cappadocia. His mother is believed to have died during childbirth, when his mother was giving birth to his sister or Mithridates V. He was born and raised in the Kingdom of Pontus. Mithridates V succeeded his paternal aunt Laodice and paternal uncle Mithridates IV of Pontus on the Pontian throne and the accession of Mithridates V is uncertain.
Mithridates V continued the politics of an alliance with the Roman Republic started by his predecessors. He supported them with some ships and a small auxiliary force during the Third Punic War (149–146 BC) and at a subsequent period rendered them useful assistance in the war against King of Pergamon, Eumenes III (131–129 BC).
For his services on this occasion, Mithridates V was rewarded by the Roman consul Manius Aquillius with the province of Phrygia. However the acts of the Roman consul were rescinded by the Roman Senate on the grounds of bribery, but it appears that he maintained his possession of Phrygia until his death. Mithridates V also increased the power of the Kingdom of Pontus by the marriage of his eldest child, his daughter Laodice of Cappadocia to King Ariarathes VI of Cappadocia. The end of his reign can only be approximately determined based on statements concerning the accession of his son Mithridates VI, which is assign in the year 120 BC to end of the reign of Mithridates V.