*** Welcome to piglix ***

Nandrolone

Nandrolone
Nandrolone.svg
Clinical data
Pronunciation /ˈnændrəln/
Pregnancy
category
Routes of
administration
Intramuscular
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability 2.24% (Oral)
100% (Intramuscular)
Metabolism Hepatic
Biological half-life 6 days
Excretion ~21 days
Identifiers
Synonyms Nortestosterone, 19-nortestosterone, 10-nortestosterone, norandrostenolone, nortestosterone, nortestrionate, nortestonate, oestrenolone, estrenolone, SG-4341
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
ECHA InfoCard 100.006.457
Chemical and physical data
Formula C18H26O2
Molar mass 274.40
3D model (Jmol)
 NYesY (what is this?)  

Nandrolone (INN, BAN), also known as 19-nortestosterone or 19-norandrostenolone, is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone. The drug itself is inactive orally due to its lack of a 17α-alkyl group (which renders it vulnerable to extensive first-pass metabolism) and is not actually employed in medicine. Instead, nandrolone is used in the form of a variety of long-acting prodrug esters (see nandrolone ester) for intramuscular injection, the most common of which are nandrolone decanoate (Deca-Durabolin, Eubolin, Retabolil) and, to a lesser extent, nandrolone phenylpropionate (Durabolin, Fenobolin).

As of 2009, nandrolone was used clinically, but increasingly rarely, for people in catabolic states who had major burns, cancer, and AIDS, and an ophthalmological formulation was available to support cornea healing.

The positive effects of the drug include muscle growth, appetite stimulation and increased red blood cell production, and bone density. Clinical studies have shown it to be effective in treating anemia, osteoporosis and some forms of neoplasia including breast cancer, and also acts as a progestin-based contraceptive.


...
Wikipedia

...