OGT (gene)

OGT
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1W3B, 3PE3, 3PE4, 3TAX, 4AY5, 4AY6, 4CDR, 4GYW, 4GYY, 4GZ3, 4GZ5, 4GZ6, 4N39, 4N3A, 4N3B, 4XI9, 4XIF, 5BNW, 5C1D
Identifiers
Aliases	OGT, HRNT1, O-GLCNAC, HINCUT-1, O-linked N-acetylglucosamine (GlcNAc) transferase
External IDs	MGI: 1339639 HomoloGene: 9675 GeneCards: OGT
Gene ontology Molecular function • lipid binding • transferase activity • acetylglucosaminyltransferase activity • transferase activity, transferring glycosyl groups • histone acetyltransferase activity (H4-K8 specific) • histone acetyltransferase activity (H4-K5 specific) • protein O-GlcNAc transferase activity • protein binding • histone acetyltransferase activity (H4-K16 specific) • phosphatidylinositol-3,4,5-trisphosphate binding • protein N-acetylglucosaminyltransferase activity Cellular component • cytoplasm • membrane • plasma membrane • mitochondrion • histone acetyltransferase complex • nucleus • cytosol • nucleoplasm Biological process • regulation of gluconeogenesis involved in cellular glucose homeostasis • response to nutrient • rhythmic process • histone H3-K4 trimethylation • protein O-linked glycosylation • regulation of Rac protein signal transduction • circadian regulation of gene expression • regulation of glycolytic process • histone H4-K5 acetylation • response to insulin • negative regulation of protein ubiquitination • protein glycosylation • positive regulation of proteolysis • positive regulation of histone H3-K27 methylation • histone H4-K16 acetylation • histone H4-K8 acetylation • phosphatidylinositol-mediated signaling • signal transduction • positive regulation of transcription from RNA polymerase II promoter • regulation of insulin receptor signaling pathway • apoptotic process • covalent chromatin modification • protein deubiquitination Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8473	108155
Ensembl	ENSG00000147162	ENSMUSG00000034160
UniProt	O15294	Q8CGY8
RefSeq (mRNA)	NM_003605 NM_181672 NM_181673	NM_001290535 NM_139144
RefSeq (protein)	NP_858058 NP_858059	NP_001277464.1 NP_631883.2 NP_001277464 NP_631883
Location (UCSC)	Chr X: 71.53 – 71.58 Mb	Chr X: 101.64 – 101.68 Mb
PubMed search

1W3B, 3PE3, 3PE4, 3TAX, 4AY5, 4AY6, 4CDR, 4GYW, 4GYY, 4GZ3, 4GZ5, 4GZ6, 4N39, 4N3A, 4N3B, 4XI9, 4XIF, 5BNW, 5C1D

8473

108155

ENSG00000147162

ENSMUSG00000034160

O15294

...
Wikipedia