ORM1

ORM1
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 3KQ0
Identifiers
Aliases	ORM1, AGP-A, AGP1, HEL-S-153w, ORM, orosomucoid 1
External IDs	HomoloGene: 128040 GeneCards: ORM1
Gene ontology Molecular function • protein binding Cellular component • blood microparticle • extracellular exosome • platelet alpha granule lumen • extracellular region • extracellular space • specific granule lumen • tertiary granule lumen Biological process • negative regulation of interleukin-6 production • negative regulation of tumor necrosis factor production • regulation of immune system process • inflammatory response • acute-phase response • transport • platelet degranulation • neutrophil degranulation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5004	n/a
Ensembl	ENSG00000229314	n/a
UniProt	P02763	n/a
RefSeq (mRNA)	NM_000607	n/a
RefSeq (protein)	NP_000598	n/a
Location (UCSC)	Chr 9: 114.32 – 114.33 Mb	n/a
PubMed search		n/a

3KQ0

5004

n/a

ENSG00000229314

n/a

P02763

n/a

NM_000607

n/a

NP_000598

n/a

Alpha-1-acid glycoprotein 1 is a protein that in humans is encoded by the ORM1 gene.

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.

ORM1 has been shown to interact with Plasminogen activator inhibitor-1.

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Wikipedia