OCLN | |||||||||||||||
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Identifiers | |||||||||||||||
Aliases | OCLN, BLCPMG, PPP1R115, occludin | ||||||||||||||
External IDs | OMIM: 602876 MGI: 106183 HomoloGene: 1905 GeneCards: OCLN | ||||||||||||||
Orthologs | |||||||||||||||
Species | Human | Mouse | |||||||||||||
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | Chr 5: 69.49 – 69.56 Mb | Chr 13: 100.5 – 100.55 Mb | |||||||||||||
PubMed search | |||||||||||||||
n/a
NM_002538
NM_001205254
NM_001205255
NP_001192183
NP_001192184
NP_002529
Occludin is a protein that in humans is encoded by the OCLN gene. Occludin is a 65-kDa (522-amino acid polypeptide -human) integral plasma-membrane protein located at the tight junctions, described for the first time in 1993 by Shoichiro Tsukita. Together with the Claudin group of proteins, it is the main component of the tight junctions.