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Occludin

OCLN
Occludin.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases OCLN, BLCPMG, PPP1R115, occludin
External IDs OMIM: 602876 MGI: 106183 HomoloGene: 1905 GeneCards: OCLN
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002538
NM_001205254
NM_001205255

NM_008756

RefSeq (protein)

NP_001192183
NP_001192184
NP_002529

NP_032782.1
NP_032782

Location (UCSC) Chr 5: 69.49 – 69.56 Mb Chr 13: 100.5 – 100.55 Mb
PubMed search

1WPA, 1XAW, 3G7C

NM_002538
NM_001205254
NM_001205255

NM_008756

NP_001192183
NP_001192184
NP_002529

NP_032782.1
NP_032782

Occludin is a protein that in humans is encoded by the OCLN gene. Occludin is a 65-kDa (522-amino acid polypeptide -human) integral plasma-membrane protein located at the tight junctions, described for the first time in 1993 by Shoichiro Tsukita. Together with the Claudin group of proteins, it is the main component of the tight junctions.


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