"Only When I Lose Myself" is Depeche Mode's thirty-fifth UK single, released on 7 September 1998, exclusive to The Singles 86>98. It is the first non-album studio single since "It's Called a Heart" in 1985, and is also one of the rare singles to have two limited editions ("L12/LCD Bong" and "XL12/XLCD Bong" - the others being "Enjoy the Silence" and "In Your Room").

There are two B-sides -- "Surrender" was the first exclusive vocal B-side since "My Joy" in 1993 from the "Walking in My Shoes" single, and the other is an instrumental titled "Headstar". A rare remix of "Painkiller" from 1997 was re-released as a B-side on some versions. The release also includes a new remix of World in My Eyes.

The music video for "Only When I Lose Myself" was directed by Brian Griffin, who had previously worked with Depeche Mode as a photographer, and did the cover art for Depeche Mode's first five albums. The soundtrack to the video is a unique version of the song, fading out at the last chorus and omitting the instrumental outro (like the radio version), but including the instrumental intro (which is missing from the radio version).

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