Progesterone receptor

PGR
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4OAR, 1A28, 1E3K, 1SQN, 1SR7, 1ZUC, 2C7A, 2OVH, 2OVM, 2W8Y, 3D90, 3G8O, 3HQ5, 3KBA, 3ZR7, 3ZRA, 3ZRB, 4A2J, 4APU, 5CC0
Identifiers
Aliases	PGR, NR3C3, PR, progesterone receptor
External IDs	MGI: 97567 HomoloGene: 713 GeneCards: PGR
Targeted by Drug
dydrogesterone, Levonorgestrel, Medroxyprogesterone, norethindrone, progesterone, promegestone, tanaproget, mifepristone, ulipristal acetate, asoprisnil
Gene ontology Molecular function • DNA binding • sequence-specific DNA binding • transcription factor activity, sequence-specific DNA binding • ATPase binding • zinc ion binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • metal ion binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • steroid hormone receptor activity • steroid binding • protein binding • enzyme binding • receptor binding • lipid binding Cellular component • cytoplasm • membrane • nucleoplasm • mitochondrial outer membrane • mitochondrion • nucleus Biological process • regulation of transcription, DNA-templated • cell-cell signaling • negative regulation of gene expression • transcription, DNA-templated • transcription initiation from RNA polymerase II promoter • signal transduction • steroid hormone mediated signaling pathway • positive regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5241	18667
Ensembl	ENSG00000082175	ENSMUSG00000031870
UniProt	P06401	Q00175
RefSeq (mRNA)	NM_000926 NM_001202474 NM_001271161 NM_001271162	NM_008829
RefSeq (protein)	NP_000917 NP_001189403 NP_001258090 NP_001258091	NP_032855
Location (UCSC)	Chr 11: 101.03 – 101.13 Mb	Chr 9: 8.9 – 8.97 Mb
PubMed search

Progesterone receptor, N-terminal
Identifiers
Symbol	Progest_rcpt_N
Pfam	PF02161
InterPro	IPR000128
Available protein structures: Pfam structures PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

4OAR, 1A28, 1E3K, 1SQN, 1SR7, 1ZUC, 2C7A, 2OVH, 2OVM, 2W8Y, 3D90, 3G8O, 3HQ5, 3KBA, 3ZR7, 3ZRA, 3ZRB, 4A2J, 4APU, 5CC0

5241

18667

ENSG00000082175

ENSMUSG00000031870

...
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