SF3B1

SF3B1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2F9D, 2F9J, 2PEH, 3LQV, 4OZ1, 2FHO
Identifiers
Aliases	SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155, splicing factor 3b subunit 1
External IDs	MGI: 1932339 HomoloGene: 6696 GeneCards: SF3B1
Gene ontology Molecular function • protein binding • mRNA binding • RNA binding Cellular component • U11/U12 snRNP • catalytic step 2 spliceosome • spliceosomal complex • U12-type spliceosomal complex • U2-type prespliceosome • nucleus • U2 snRNP • nucleoplasm • nuclear speck Biological process • RNA splicing, via transesterification reactions • positive regulation of gene expression, epigenetic • mRNA splicing, via spliceosome • spliceosomal complex assembly • mRNA processing • RNA splicing Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23451	81898
Ensembl	ENSG00000115524	ENSMUSG00000025982
UniProt	O75533	Q99NB9
RefSeq (mRNA)	NM_001005526 NM_001308824 NM_012433	NM_031179
RefSeq (protein)	NP_001005526 NP_001295753 NP_036565	n/a
Location (UCSC)	Chr 2: 197.39 – 197.44 Mb	Chr 1: 54.99 – 55.03 Mb
PubMed search

2F9D, 2F9J, 2PEH, 3LQV, 4OZ1, 2FHO

23451

81898

ENSG00000115524

ENSMUSG00000025982

O75533

Q99NB9

NM_001005526
NM_001308824
NM_012433

NM_031179

NP_001005526
NP_001295753
NP_036565

n/a

Splicing factor 3B subunit 1 is a protein that in humans is encoded by the SF3B1 gene.

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