SLC22A2
Solute carrier family 22 member 2 is a protein that in humans is encoded by the SLC22A2 gene.
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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