TXNRD1

TXNRD1

Protein TXNRD1 PDB 1h6v.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2CFY, 2J3N, 2ZZ0, 2ZZB, 2ZZC, 3QFA, 3QFB

Identifiers

TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR, thioredoxin reductase 1

External IDs

MGI: 1354175 HomoloGene: 55733 GeneCards: TXNRD1

Gene ontology
Molecular function	• protein disulfide oxidoreductase activity • methylselenol reductase activity • flavin adenine dinucleotide binding • methylseleninic acid reductase activity • protein binding • electron carrier activity • oxidoreductase activity • oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor • thioredoxin-disulfide reductase activity
Cellular component	• cytoplasm • extracellular exosome • nucleus • fibrillar center • nucleoplasm • mitochondrion • cytosol
Biological process	• nucleobase-containing small molecule interconversion • selenium compound metabolic process • oxidation-reduction process • signal transduction • cellular oxidant detoxification • response to oxygen radical • cell redox homeostasis • regulation of lipid metabolic process • cellular response to oxidative stress • mesoderm formation • gastrulation • cell proliferation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


7296


50493


ENSG00000198431


ENSMUSG00000020250


Q16881


Q9JMH6

RefSeq (mRNA)

NM_182743 NM_001093771 NM_001261445 NM_001261446 NM_003330
NM_182729 NM_182742


NM_001042513 NM_001042514 NM_001042523 NM_015762

RefSeq (protein)

NP_001087240 NP_001248374 NP_001248375 NP_003321 NP_877393
NP_877419 NP_877420


NP_001035978 NP_001035979 NP_001035988 NP_056577

Location (UCSC)

Chr 12: 104.22 – 104.35 Mb

Chr 10: 82.83 – 82.9 Mb

PubMed search

2CFY, 2J3N, 2ZZ0, 2ZZB, 2ZZC, 3QFA, 3QFB

ENSG00000198431

ENSMUSG00000020250

NM_182729
NM_182742

NM_001042513
NM_001042514
NM_001042523
NM_015762

NP_877419
NP_877420

NP_001035978
NP_001035979
NP_001035988
NP_056577

...
Wikipedia

...