| U.S. Route 53 | |||||||
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U.S. 53 highlighted in red
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| Route information | |||||||
| Length: | 403 mi (649 km) | ||||||
| Existed: | 1926 – present | ||||||
| Major junctions | |||||||
| South end: |
at La Crosse, WI |
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| North end: |
at Fort Frances, ON |
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| Location | |||||||
| States: | Wisconsin, Minnesota | ||||||
| Counties: |
WI: La Crosse, Trempealeau, Eau Claire, Chippewa, Barron, Washburn, Douglas MN: St. Louis, Koochiching |
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| Highway system | |||||||
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I-90 at La Crosse, WI
I-94 at Eau Claire, WI
US 12 at Altoona, WI
WIS 29 at Lake Hallie, WI
US 63 at Spooner, WI
US 2 at Superior, WI![]()
I-35 / I-535 at Duluth, MN
MN 33 at Independence, MN![]()
US 169 / MN 169 at Virginia, MN