| U.S. Route 54 | ||||
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| Maintained by MoDOT | ||||
| Length: | 279 mi (449 km) | |||
| Existed: | 1927 – present | |||
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I-49 in Nevada![]()
US 50 / US 63 in Jefferson City
I-70 in Kingdom City
U.S. Route 54 (US 54) is a west-east highway that starts from the Kansas state line in Nevada to the Illinois state line in Louisiana.