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Eggshell membrane


Eggshell membrane is a dietary supplement made from chicken eggs, having the objective of reducing or treating osteoarthritis or other stiffness and pain of the joints.

The membrane is the clear film lining the eggshell, visible when one peels a boiled egg. Eggshell membrane is primarily composed of fibrous proteins such as collagen type I. However, eggshell membranes have also been shown to contain glycosaminoglycans, such as dermatan sulfate and chondroitin sulfate and sulfated glycoproteins including hexosamines, such as glucosamine. Other components identified in eggshell membranes are hyaluronic acid, sialic acid, desmosine and isodesmosine, ovotransferrin, lysyl oxidase, lysozyme, and β-N-acetylglucosaminidase.

Eggshell membrane is commercially derived from the eggshells of industrial egg processors. In the United States, egg-breaking facilities generate more than 24 billion eggshells every year. There are various ways in which the membrane of an eggshell is separated from the shell, including chemical, mechanical, steam and vacuum processes: see Eggshell and protein membrane separation. The isolated membrane is then partially hydrolyzed and dried to produce a powder, distributed as eggshell membrane (EM).



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Elemental calcium


Elemental calcium is a term used in dietary supplement ingredient lists to refer to the amount of calcium in a product. Calcium pills contain calcium in a variety of molecules, such as carbonate, citrate, citrate-maleate, orotate, etc. Each pill supplies a different amount of elemental calcium when absorbed, and hence differs in its effectiveness. For example, calcium carbonate is 40% elemental calcium by weight; citrate is roughly 20% calcium, etc. Thus a 500 mg pill of calcium carbonate contains 200 mg of calcium and the container will indicate each pill has 200 mg of elemental calcium. This is the calcium that is actually available to the body and, as such, is the amount that one needs to consider towards his/her daily requirement. Hence, one should read the label carefully to determine the number of pills to be taken. Other factors may influence the choice of molecule prescribed. Calcium carbonate is by far the best, since it is cheap and allows more calcium intake per dose, but leads to indigestion, flatulence and other intestinal problems in quite a few patients. It also requires that the patient take the tablet after a full meal and avoid taking antacids concomitantly, which is difficult to achieve in patients taking multiple medications. Citrate or citrate-maleate is the molecule of choice in such cases; these need to be taken before meals and have less/no interaction with antacids.



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Emergen-C


Emergen-C is an effervescent, powdered drink mix vitamin supplement manufactured by Alacer Corp. The Emergen-C product line was introduced in 1978. Alacer was established as a private company in 1972, focusing on vitamin supplements containing vitamin C. In 2012, the company was acquired by Pfizer.

It contains, depending on the variety, 16 times the vitamin C, 4 times the vitamin B12, and 5 times the vitamin B6 of the USDA Reference Daily Intake based on a 2000 calorie diet. The efficacy of vitamin C megadoses as a cold remedy has not been firmly established in the scientific literature.

Emergen-C is available in a variety of flavors. Some flavors also include additional supplements, such as calcium, glucosamine, quercetin, or lycopene.

Alacer manufactures its products in the United States, in Carlisle, Pennsylvania.

GMO ingredients are used . From the Alacer website: "We have chosen to source materials that are non-GMO whenever possible. That being said, we cannot guarantee that all of our raw materials are sourced from non-GMO ingredients and do not currently have this requirement in place for our vendors". Most products do not contain animal-derived ingredients, but some certain products contain chondroitin from cows, honey, and vitamin D3 from wool.

In December 2013, a superior court judge preliminarily approved a $6.45 million settlement to a class-action lawsuit filed against Alacer Corp. for alleged deceptive marketing. The complaint, which was originally filed earlier in the year, alleged that the company misleadingly represented that the supplement would provide health benefits – including reducing the risk of or preventing colds and flu – without scientific evidence to support such claims. According to the settlement terms, class members may receive a refund of up to $36 with proof of purchase. (Wong et al v. Alacer Corp., Case No. CGC-12-519221, Superior Court of California County of San Francisco). A superior court judge gave final approval of the settlement to this lawsuit in June 2014.



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Emu oil


Emu oil is an oil derived from adipose tissue harvested from certain subspecies of the emu, Dromaius novaehollandiae, a flightless bird indigenous to Australia.

Unadulterated emu oil can vary widely in color and viscosity anywhere from an off-white creamy texture to a thin yellow liquid, depending on the diet of the emu and the refining method(s) used. Industrially refined "emu grade" emu oil is composed of a minimum of 70% unsaturated fatty acids. The largest component is oleic acid, a monounsaturated omega-9 fatty acid. Emu oil also contains roughly 20% linoleic acid (an omega-6 fatty acid) and 1-2% linolenic acid (an omega-3 fatty acid). Fully refined emu oil has a bland flavor.

Emu oil has previously been wrongly promoted as a dietary supplement with the claim it can treat a variety of human ailments, including cancer and arthritis.

Commercial emu oil supplements are not standardized and vary widely in their potency. The U.S. Food and Drug Administration highlighted emu oil in a 2009 article on "How to Spot Health Fraud," pointing out that many "pure emu oil" products are unapproved drugs.

As of 2015 there have been two small human studies. One looked at emu oil as a skin moisturizer and the other as an insect repellent. The papers published from these studies note emu oil's future potential, citing "its possible antidiabetic activity" as "an attractive pharmacologic agent to further explore for its therapeutic activity to treat various ailments."



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Energy bar


Energy bars are supplemental bars containing cereals and other high energy foods targeted at people who require quick energy but do not have time for a meal. They are different from energy drinks, which contain caffeine, whereas bars provide food energy.

Energy in food comes from three sources: fat, protein, and carbohydrates. A typical energy bar weighs between 45 and 80 g and is likely to supply about 200–300 Cal (840–1,300 kJ), 3–9 g of fat, 7–15 g of protein, and 20–40 g of carbohydrates.

In order to provide energy quickly, most of the carbohydrates are various types of sugars like fructose, glucose, maltodextrin, dextrose and others in various ratios. Use of complex carbohydrate sources like oats and barley is limited and such carbohydrate sources are mostly used in protein bars. Proteins come mostly in the form of fast digesting whey protein. Energy bars generally don't contain sugar alcohols, since these bars, due to type of carbohydrate content, don't require low calorie sweeteners to improve their taste. Fats in energy bars are kept to minimum and their main sources are often cocoa butter and dark chocolate.

Energy bars are used as energy source during athletic events like marathon, triathlon and other events and outdoor activities, where energy expenditure is high, for longer period of time.



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Energy gel


Energy gels are carbohydrate gels that provide energy for exercise and promote recovery, commonly used in endurance events such as running, cycling, and triathlons. Energy gels are also referred to as endurance gels, sports gels, nutritional gels, and carbohydrate gels. They come in small, single-serve plastic packets. Each packet has a strip with a small notch at the top that can be peeled off to reveal an opening through which the gel can be consumed.

Sports energy gels emerged in the United Kingdom in 1986 as a "convenient, prewrapped, portable" way to deliver carbohydrates during endurance events. Gels have a gooey texture and are sometimes referred to as "goo" generically. The gel Leppin Squeezy was distributed at the Hawaii Ironman Triathlon in 1988. Once considered a "cult product in clear packaging", energy gel products are now marketed in fancy packaging and come in a variety of flavors. The energy gel market grew during the 1990s, as professional athletes began endorsing products. Manufacturers generally encourage the consumption of multiple packets, with water, when participating in endurance events. Individual packets typically cost between 99 cents and $1.29 (as reported by the St. Petersburg Times in 2003).

Once consumed, the carbohydrates found in the gels are absorbed into the blood to supply the body with calories and nutrients to fuel exercise activity by helping to delay muscular fatigue, raise blood sugar levels, and enhance performance. Most energy gels have no fat, fiber, or protein, so they can be digested quickly. They contain mainly sugars and maltodextrins, which make them similar to sports drinks without the water. Since simple carbohydrates slow down gastric emptying and can cause gastrointestinal distress in athletes, there are attempts to create new categories of energy gels made with complex, long chain carbohydrates and/or fat. Spring gel is an example of a gel with low sugar, low glycemic index carbohydrate content with the addition of fat and Vespapower is an example of a gel made with fat. Some gels, such as e-Gel, also come with added electrolytes. There are also gels with extras such as ginseng and other herbs, amino acids, vitamins, and Coenzyme Q10.Caffeine can be found in some gels as well. Examples of common energy gels are GU,PowerBar Gel, and Clif Shot.



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Enforcement actions against a%C3%A7a%C3%AD berry supplement manufacturers



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Ensure


imageEnsure

Ensure is the brand name of nutritional supplements and meal replacements manufactured by Abbott Laboratories.

In 1903, Harry C. Moores and Stanley M. Ross launch the "Moores & Ross Milk Company" which specialized in bottling milk for home delivery for the first few years. By 1964, however, the company merged with Abbott Laboratories. A drink called Ensure was first marketed by Ross Laboratories in 1973.

In the 1990s Ensure and other nutritional drink products like Mead Johnson's Sustacal and Nestlé's Boost and Resource brands were fiercely competing to capture market share among healthy adults. In 1996 Ensure had sales of about $300 million and accounted for 80% of protein supplement sales; Abbott spent $45.4 million to advertise Ensure during the first nine months of 1996, around 70% more than it spent during the same period of 1995. In 1995 the Center for Science in the Public Interest said that ads for Ensure were "the most misleading food ad" of that year. In 1997 Abbott settled charges from the Federal Trade Commission that it was falsely marketing Ensure as having a similar amount of vitamins as multivitamin supplements, as being recommended by doctors more than any other nutritional supplement, and as being recommended by doctors as a way to stay healthy and active for people who were otherwise healthy.

Ensure has been used in the force feeding of hunger-striking prisoners at the United States' Guantanamo Bay detention camps.

When Abbott split off its pharmaceuticals division, Abbvie, in 2013, the Ensure product line remained with Abbott with the other nutritional products.

As of 2016, variants of Ensure included:

As of 2016, Ensure Complete had been discontinued.




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Enzyte


Enzyte is an herbal nutritional supplement originally manufactured by Berkeley Premium Nutraceuticals (now Vianda, LLC) of Cincinnati, Ohio. The manufacturer has claimed that Enzyte promotes "natural male enhancement," which is a euphemism for enhancing erectile function. However, its effectiveness has been called into doubt and the claims of the manufacturer have been under scrutiny from various state and federal organizations. Kenneth Goldberg, M.D., medical director of the Male Health Center at Baylor University, says, "It makes no sense medically. There's no way that increasing blood flow to the penis, as Enzyte claims to do, will actually increase its size."

In March 2005, following thousands of consumer complaints to the Better Business Bureau, federal agents raided Berkeley facilities, gathering material that resulted in a 112-count criminal indictment. The company's founder and CEO, Steven M Warshak and his mother, Harriet Warshak, were found guilty of conspiracy to commit mail fraud, bank fraud, and money laundering, and in September 2008 they were sentenced to prison and ordered to forfeit $500 million in assets. The convictions and fines forced the company into bankruptcy, and in December 2008 its assets were sold for $2.75 million to investment company Pristine Bay, which continued operations.

Enzyte is widely advertised on U.S. television as "the once daily tablet for natural male enhancement." The commercials feature a character known as "Smilin' Bob," acted out by Canadian actor Andrew Olcott, who, in the commercials, always wears a smile that is implied to be caused by the enhancing effects of Enzyte; these advertisements feature double entendres. Some such commercials also feature an equally smiling "Mrs. Bob." (Olcott, who was married and a father in real life, was also a visual artist, and he later owned and operated a small advertising firm.)

Because Enzyte is an herbal product, no testing is required by the U.S. Food and Drug Administration. An official of the Federal Trade Commission division that monitors advertising says the lack of scientific testing is "a red flag right away. There's no science behind these claims." The company has conceded that it has no scientific studies that substantiate any of its Enzyte claims.



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Ephedra


Ephedra is a medicinal preparation from the plant Ephedra sinica. Several additional species belonging to the genus Ephedra have traditionally been used for a variety of medicinal purposes, and are a possible candidate for the Soma plant of Indo-Iranian religion. It has been used in traditional Chinese medicine for more than 2,000 years.Native Americans and Mormon pioneers drank a tea brewed from other Ephedra species, called "Mormon tea" and "Indian tea".

In recent years, dietary supplements containing ephedra alkaloid have been found to be unsafe, with reports of serious side effects and ephedra-related deaths. In response to accumulating evidence of adverse effects and deaths related to ephedra, the U.S. Food and Drug Administration (FDA) banned the sale of supplements containing ephedrine alkaloids in 2004. The ban was challenged in court by ephedra manufacturers, but ultimately upheld in 2006 by the U.S. Court of Appeals for the Tenth Circuit. Ephedra extracts not containing ephedrine have not been banned by the FDA and are still sold legally today.

A wide variety of alkaloid and non-alkaloid compounds have been identified in various species of ephedra. Of the six ephedrine-type ingredients found in ephedra (at concentrations of 0.02-3.4%), the most common are ephedrine and pseudoephedrine. The stimulant and thermogenic effects of Ephedra sinica and other ephedra species are due to the presence of the alkaloids ephedrine and pseudoephedrine. These compounds stimulate the brain, increase heart rate, constrict blood vessels (increasing blood pressure), and expand bronchial tubes (making breathing easier). Their thermogenic properties cause an increase in metabolism, as evidenced by an increase in body heat.



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