Mequinol
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| Clinical data | |
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| AHFS/Drugs.com | International Drug Names |
| MedlinePlus | a682437 |
| Routes of administration |
Topical |
| ATC code | |
| Legal status | |
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| Identifiers | |
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| Synonyms | 4-Hydroxyanisole; para-Guaiacol |
| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
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| KEGG | |
| ChEMBL | |
| ECHA InfoCard | 100.005.246 |
| Chemical and physical data | |
| Formula | C7H8O2 |
| Molar mass | 124.13722 g/mol |
| Density | 1.55 g/cm3 |
| Melting point | 52.5 °C (126.5 °F) |
| Boiling point | 243 °C (469 °F) |
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Mequinol, MEHQ or 4-Methoxyphenol, is a phenol used in dermatology and organic chemistry.
Mequinol is a common active ingredient in topical drugs used for skin depigmentation. As a topical drug Mequinol is often mixed with tretinoin, a topical retinoid. A common formulation for this drug is an ethanolic solution of 2% Mequinol and 0.01% tretinoin by mass.Dermatologists commonly prescribe the drug to treat solar lentigines, liver spots, or age spots.
Lower dosages of mequinol have been used in conjunction with a Q-switched laser to depigment skin in patients with disseminated idiopathic vitiligo.
In organic chemistry 4-methoxyphenol is used to inhibit the radical polymerization of monomers (e.g. acrylates or styrene monomers).
4-Methoxyphenol is produced from p-benzoquinone and methanol via a free radical reaction.
People can be exposed to 4-methoxyphenol in the workplace by breathing it in, skin absorption, swallowing it, skin contact, and eye contact. The National Institute for Occupational Safety and Health (NIOSH) has set a recommended exposure limit (REL) of 5 mg/m3 over an 8-hour workday.
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